gene_symbol
IL3RA
hgnc_id
HGNC:6012
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
AFM28 cross-links CD123 on target cells with CD16A on NK cells (and macrophages), activating ADCC and causing lysis of CD123+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-associated antigen on AML blasts
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05817058
disease_id_num_tar_ref
5192
drug_id_num_tar_ref
14077