gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19 CAR-T cells bind CD19 on B-lineage cells, form an immune synapse, and kill targets via perforin/granzyme-mediated cytolysis (and death-receptor pathways), depleting CD19+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06056921
disease_id_num_tar_ref
5196
drug_id_num_tar_ref
14087