gene_symbol
FCRL5
hgnc_id
HGNC:18508
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells recognize FcRL5 on target cells; CAR engagement activates CD3ζ/costimulatory signaling, triggering perforin/granzyme-mediated cytolysis (and death receptor pathways) of FcRL5-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as CD307e/IRTA2; cell-surface antigen on B-lineage plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06196255
disease_id_num_tar_ref
5200
drug_id_num_tar_ref
14091