gene_symbol
MICA
hgnc_id
HGNC:7090
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Vγ9Vδ2 T cells express NKG2D that binds MICA on target cells, activating an immune synapse and inducing perforin/granzyme-mediated apoptosis (with supportive cytokine release).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D stress ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06396481
disease_id_num_tar_ref
446
drug_id_num_tar_ref
1260