gene_symbol
MICB
hgnc_id
HGNC:7091
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
MICB engages NKG2D on Vγ9Vδ2 T cells, activating them to release perforin/granzymes and kill the target cell.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D stress ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06396481
disease_id_num_tar_ref
446
drug_id_num_tar_ref
1260