gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR T cells bind CD19 on target cells and kill them via perforin/granzyme-mediated cytotoxicity and immune effector mechanisms after CAR activation.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Membrane B-cell lineage antigen; HLA-independent CAR recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05950802
disease_id_num_tar_ref
5227
drug_id_num_tar_ref
14183