gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-BCMA CAR T cells bind BCMA on target cells, activate, and kill them via T cell cytotoxic mechanisms (perforin/granzyme-mediated apoptosis and related death receptor pathways).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Dual-epitope VHH binder; CAR with 4-1BB costimulatory domain
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06577025
disease_id_num_tar_ref
5238
drug_id_num_tar_ref
14228