gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Teclistamab binds CD3 on T cells to activate them and redirect cytotoxicity toward BCMA-positive myeloma cells; killing occurs via perforin/granzyme-mediated lysis of BCMA+ targets, not CD3+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell engaging arm
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06577025
disease_id_num_tar_ref
5238
drug_id_num_tar_ref
14231