gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Vaccine-primed/infused CD8+ T cells recognize the tumor peptide–HLA class I complex via the TCR and kill target cells via perforin/granzyme-mediated cytotoxicity (±Fas–FasL), supported by IFN-γ–driven Th1 responses.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Multiple TAAs; HLA-A/B/C restricted on tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06277154
disease_id_num_tar_ref
5273
drug_id_num_tar_ref
14344