gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
DC vaccination primes tumor-specific T cells; these T cells recognize the tumor peptide–HLA class II complex via the TCR and kill target cells mainly via perforin/granzyme (with IFN-γ–driven Th1 responses and Fas/FasL contributing).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Multiple TAAs; HLA-DR/DP/DQ restricted, primarily on dendritic cells for T-cell priming
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06277154
disease_id_num_tar_ref
5273
drug_id_num_tar_ref
14344