gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine peptides are presented by APCs to prime/expand CMV pp65–specific CD8+ T cells (with CD4 help). These CTLs recognize pp65 peptide–HLA-A*02:01 complexes on target cells and kill them via perforin/granzyme-mediated apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
HLA-A*0201–restricted CD8 epitope; viral antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05283109
disease_id_num_tar_ref
5285
drug_id_num_tar_ref
14379