gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
P30 is a CD4 helper epitope used to provide T-cell help for priming CTLs. The vaccine induces CD8+ T cells that kill cells presenting EphA2, survivin, or CMV pp65 via MHC I–mediated cytolysis; cells presenting the P30 helper epitope are not directly targeted for killing.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD4 helper epitope; HLA class II–restricted (promiscuous HLA-DR)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05283109
disease_id_num_tar_ref
5285
drug_id_num_tar_ref
14379