gene_symbol
UNKNOWN
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Vγ9Vδ2 T cells expressing CD16 (FcγRIIIa) bind IgG Fc on opsonized tumor cells, triggering ADCC and perforin/granzyme-mediated killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
On
other_modifier
ADCC via CD16 (FCGR3A) on Vγ9Vδ2 T cells; requires therapeutic antibody coating
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06396481
disease_id_num_tar_ref
446
drug_id_num_tar_ref
1260