gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
EBV-specific TCR-T cells recognize EBV-derived peptide presented on HLA-A*02:01 on target cells and directly induce apoptosis via perforin/granzyme release and Fas–FasL signaling.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
peptide–MHC class I (pMHC) complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06135922
disease_id_num_tar_ref
5291
drug_id_num_tar_ref
14395