gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The mRNA vaccine primes neoantigen-specific CD8+ T cells; these CTLs recognize the neoantigen peptide presented on MHC I by tumor cells and kill them via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented by HLA-A/B/C alleles on APCs and tumor cells; recognized by CD8+ TCRs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06026800
disease_id_num_tar_ref
5303
drug_id_num_tar_ref
14426