gene_symbol
CTAG1B
hgnc_id
HGNC:2491
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Engineered NK cells expressing an NY-ESO-1–specific, HLA-A*02–restricted TCR recognize peptide–HLA on target cells and directly kill them via cytotoxic degranulation (perforin/granzymes) and death-receptor pathways.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–HLA complex; restriction to HLA-A*02 (e.g., HLA-A*02:01)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06083883
disease_id_num_tar_ref
5317
drug_id_num_tar_ref
14469