gene_symbol
ULBP2
hgnc_id
HGNC:14894
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D-CAR T cells recognize ULBP2 on target cells, triggering CAR signaling and T-cell effector functions that kill the bound cell via perforin/granzyme release and death-receptor–mediated apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Stress-induced NKG2D ligand on tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06087341
disease_id_num_tar_ref
5319
drug_id_num_tar_ref
14474