gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-expressing macrophages bind the tumor-associated antigen and directly engulf and kill antigen-positive cells via CAR-triggered phagocytosis and phagolysosomal/ROS-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Specific antigen not specified in the trial; CAR-M mediates MHC-independent recognition of lymphoma cell antigens
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06541327
disease_id_num_tar_ref
5328
drug_id_num_tar_ref
14503