gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused TILs recognize neoantigen peptide–HLA class I complexes via native TCRs and directly kill target cells through perforin/granzyme-mediated cytotoxicity (and death-receptor pathways).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD8+ TCR recognition of patient-specific mutated peptides bound to HLA-A/B/C
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06541327
disease_id_num_tar_ref
5328
drug_id_num_tar_ref
14505