gene_symbol
PLAUR
hgnc_id
HGNC:9053
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
uPAR-binding antibody delivers 177Lu beta radiation to bound cells, causing ionizing radiation–induced DNA double-strand breaks and cell death (with crossfire to nearby cells).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06617169
disease_id_num_tar_ref
5341
drug_id_num_tar_ref
14534