gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize CD19 on target cells and induce cytolysis via perforin/granzyme release (and death-receptor pathways), eliminating CD19+ cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen on malignant and normal B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06027957
disease_id_num_tar_ref
5357
drug_id_num_tar_ref
14569