gene_symbol
HLA-A
hgnc_id
HGNC:4931
binding_type
other
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Peptide vaccine induces TAA-specific CD8+ T cells (with Th1 help); CTLs recognize TAA peptides presented on HLA-A2 on tumor cells and kill via perforin/granzyme. HLA-A2 itself is only the restriction element, not the cytotoxic target.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Restriction element that binds and presents EO2040 CD8 epitopes on antigen-presenting cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05350501
disease_id_num_tar_ref
5370
drug_id_num_tar_ref
14613