gene_symbol
CD28
hgnc_id
HGNC:1653
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CC312 binds CD28 (and CD3) on T cells to costimulate and engage them to kill CD19+ B cells; CD28+ T cells are not targeted for cytotoxic killing and are activated rather than killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell costimulatory receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06037018
disease_id_num_tar_ref
5413
drug_id_num_tar_ref
14726