gene_symbol
CD33
hgnc_id
HGNC:1659
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-engineered NK cells bind CD33 on target cells, activating NK cytotoxicity and killing via perforin/granzyme-mediated lysis/apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as Siglec-3; myeloid differentiation antigen on AML blasts
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05987696
disease_id_num_tar_ref
5416
drug_id_num_tar_ref
14730