Skip to main content
gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells recognize CD19 on B cells and directly kill them via T‑cell cytotoxic pathways (perforin/granzyme release and Fas–FasL–mediated apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface marker (pan–B cell antigen)
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06690359
disease_id_num_tar_ref
5417
drug_id_num_tar_ref
14736