gene_symbol
IL13RA2
hgnc_id
HGNC:5975
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells recognize IL13RA2 on target cells, triggering T-cell activation and killing via perforin/granzyme-mediated cytolysis (and Fas–FasL), with supportive cytokine release.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor overexpressed on glioma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06355908
disease_id_num_tar_ref
460
drug_id_num_tar_ref
1289