gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Dinutuximab binds GD2 on target cells; its Fc engages FcγR-expressing effector cells to mediate ADCC and activates complement to induce CDC, causing lysis of GD2+ cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
glycolipid ganglioside
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06172296
disease_id_num_tar_ref
5482
drug_id_num_tar_ref
14909