gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The antibody binds Env on infected cell surfaces and recruits FcγR-expressing effector cells to mediate ADCC/ADCP, leading to clearance of infected cells; it also neutralizes virions by blocking Env–CD4 interaction.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Viral envelope antigen on virions/infected cells; binding blocks Env–CD4 interaction
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05300035
disease_id_num_tar_ref
466
drug_id_num_tar_ref
1302