gene_symbol
RAET1E
hgnc_id
HGNC:16793
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR-NK cells recognize ULBP4 (an NKG2D ligand) on target cells, triggering NK activation and killing via immune synapse–mediated degranulation (perforin/granzyme) and death-receptor pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Stress-induced NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06478459
disease_id_num_tar_ref
5509
drug_id_num_tar_ref
14997