gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR-expressing double-negative T cells recognize CD19 on target cells and induce cytotoxicity via perforin/granzyme release and death receptor (e.g., Fas/FasL) pathways, causing lysis/apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface B-lineage antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06340490
disease_id_num_tar_ref
5521
drug_id_num_tar_ref
15023