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gene_symbol
UNKNOWN
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The TLR agonist component activates dendritic cells to process and present vaccine antigens, inducing tumor-specific CD8+ T cells that kill antigen-expressing cancer cells; TLR-expressing APCs are activated, not directly killed by the drug.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Self-adjuvanting TLR peptide agonist; exact TLR subtype not disclosed
trial_id_tar_ref
drug_id_tar_ref
nct_id_tar_ref
NCT05846516
disease_id_num_tar_ref
5560
drug_id_num_tar_ref
15136