gene_symbol
HLA-DQB1
hgnc_id
HGNC:4944
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine delivers peptides and a TLR agonist to dendritic cells to enhance MHC I/II presentation, priming CD8+ T cells that then kill tumor cells; HLA‑DQ–expressing APCs are not directly targeted or killed.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide loading for CD4+ T-cell priming
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05846516
disease_id_num_tar_ref
5560
drug_id_num_tar_ref
15137