gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Adoptively transferred TILs recognize the neoantigen–HLA class I complex via their native TCRs and directly induce tumor-cell death through perforin/granzyme-mediated apoptosis, with contributions from Fas–FasL and cytokine-mediated cytotoxicity.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD8+ TCR recognition; patient-specific HLA-A/B/C restriction
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06643910
disease_id_num_tar_ref
5569
drug_id_num_tar_ref
15165