gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused TILs recognize tumor peptide–HLA class I via native TCRs and directly kill targets through perforin/granzyme-mediated apoptosis (with contributions from Fas–FasL and cytokine-mediated cytotoxicity).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD8+ TCR recognition; patient-specific HLA-A/B/C restriction
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06643910
disease_id_num_tar_ref
5569
drug_id_num_tar_ref
15165