gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused TILs recognize the tumor-associated peptide–HLA class II complex via native TCRs and kill the presenting cell through perforin/granzyme release (and Fas–FasL/cytokine-mediated apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD4+ TCR recognition; patient-specific HLA-DR/DQ/DP restriction
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06643910
disease_id_num_tar_ref
5569
drug_id_num_tar_ref
15165