gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
DC vaccine primes/expands neoantigen-specific CD8+ T cells, which recognize HLA-I–presented neoantigen on tumor cells and kill them via TCR-mediated cytolysis (perforin/granzyme and Fas–FasL pathways).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented on HLA-A/B/C to CD8+ T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06752057
disease_id_num_tar_ref
470
drug_id_num_tar_ref
1310