gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells recognize the B-cell surface antigen via the CAR and directly kill the bound B cell through T-cell effector functions (perforin/granzyme cytolysis and death receptor–mediated apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Target antigen not specified in trial; CAR-T intended to deplete B cells/plasma-lineage cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06661811
disease_id_num_tar_ref
5586
drug_id_num_tar_ref
15199