gene_symbol
CD5
hgnc_id
HGNC:1685
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD5-targeted CAR T cells bind CD5, activate via CD3zeta/co-stimulatory signaling, and kill CD5+ cells through perforin/granzyme release and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell surface antigen on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06420076
disease_id_num_tar_ref
5612
drug_id_num_tar_ref
15268