gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific antibody binds CD3 on T cells and EpCAM on tumor cells, forming an immune synapse that activates T cells to kill EpCAM-positive cells via perforin/granzyme and cytokines; CD3+ T cells themselves are not the cytotoxic target.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Binds the CD3 complex on T lymphocytes (subunit not specified in trial info)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06093698
disease_id_num_tar_ref
5616
drug_id_num_tar_ref
15278