gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BAFF-ligand CAR-T cells bind BCMA on target cells, triggering CAR signaling and T-cell cytotoxicity via perforin/granzyme release and cytokine/Fas-mediated apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TNFR superfamily member
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05546723
disease_id_num_tar_ref
5631
drug_id_num_tar_ref
15315