gene_symbol
TNFRSF13B
hgnc_id
HGNC:18153
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BAFF-ligand CAR-T cells bind TACI on target cells, activate CAR signaling, form a cytolytic synapse, and kill via perforin/granzyme release and cytokine-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as transmembrane activator and CAML interactor; TNFR superfamily member
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05546723
disease_id_num_tar_ref
5631
drug_id_num_tar_ref
15315