gene_symbol
CEACAM6
hgnc_id
HGNC:1818
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The Y-90–labeled anti-CD66 (BW250/183) antibody binds CEACAM6 (CD66c) on target cells and delivers beta radiation that induces DNA damage (double‑strand breaks) leading to cell death.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD66 family member expressed on myeloid/granulocytic cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT04856215
disease_id_num_tar_ref
5648
drug_id_num_tar_ref
15344