gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells recognize CD19 on B-lineage cells and directly kill them via T-cell cytotoxic mechanisms, primarily perforin/granzyme-mediated apoptosis (and death-receptor signaling).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Extracellular surface antigen on B-lineage cells recognized by CAR scFv
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06222853
disease_id_num_tar_ref
474
drug_id_num_tar_ref
1317