gene_symbol
HLA-A
hgnc_id
HGNC:4931
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Engineered EBV-specific TCRs recognize the EBV peptide–HLA-A*24:02 complex on target cells, triggering immune synapse formation and perforin/granzyme-mediated killing (with possible Fas/FasL apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Class I peptide–HLA complex; viral (EBV) peptide; restriction allele HLA-A*24:02
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06119256
disease_id_num_tar_ref
5665
drug_id_num_tar_ref
15390