gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Rituximab binds CD20 on B cells and kills them via Fc-mediated ADCC by NK cells/macrophages, complement-dependent cytotoxicity (C1q activation), and direct apoptotic signaling upon CD20 ligation/crosslinking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface B-cell antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05951959
disease_id_num_tar_ref
5668
drug_id_num_tar_ref
15395