gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD20 on target cells, activate, and kill via immunologic synapse with perforin/granzyme-mediated cytolysis and death-receptor (Fas/FasL) apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; non-HLA restricted
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06160362
disease_id_num_tar_ref
5673
drug_id_num_tar_ref
15408