gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti‑CD20 antibody binds CD20 on B cells and induces killing via enhanced FcγRIIIa-mediated ADCC (NK cells), antibody‑dependent phagocytosis (macrophages), and direct caspase‑independent apoptosis; complement has a minor role.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type II anti-CD20 epitope; reduced complement dependence
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05845762
disease_id_num_tar_ref
5674
drug_id_num_tar_ref
15411