gene_symbol
CD7
hgnc_id
HGNC:1695
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD7 CAR T cells bind CD7 on target cells, form an immune synapse, and kill via T cell–mediated cytotoxicity (perforin/granzyme release and death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface transmembrane glycoprotein on T/NK cells; CAR binds extracellular domain on malignant T/NK cells and a subset of AML blasts
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05377827
disease_id_num_tar_ref
5675
drug_id_num_tar_ref
15412