gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 CAR-T cells bind CD20 on B cells and induce T-cell–mediated killing via perforin/granzyme and death-receptor pathways, leading to apoptosis/lysis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface B-cell antigen targeted by CAR-T
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05784441
disease_id_num_tar_ref
5676
drug_id_num_tar_ref
15413