gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The anti-Env antibody binds HIV-1 Env on infected cells and engages Fc effector functions—NK cell–mediated ADCC, macrophage ADCP, and complement-dependent cytotoxicity—leading to killing/clearance of Env-expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Viral protein on HIV virions and infected cell surface; exact epitope not specified in the trial record
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06032546
disease_id_num_tar_ref
5698
drug_id_num_tar_ref
15475